It is extremely important to keep your denture clean.  Keeping a denture clean is not a difficult task.  The best method for cleaning your denture is gentle scrubbing with a denture brush and dishwashing detergent (such a Dawn).  The detergent is gentle and non-abrasive.  At night, before you retire, I suggest using a plastic bowl filled with warm (not hot) and detergent.  Scrub your denture off thoroughly inside and out.  When handling your dentures, stand over a clean, folded towel or a sink full of water.  This way, if you accidentally drop your dentures, they are less likely to break.  Rinse well and store the denture in water.  It is not a good idea to leave your dentures on the counter to dry out.  Dentures that are not kept wet will dry out and may lose their shape or begin to crack.

If you notice that your denture is collecting stain despite thorough cleaning, then the denture can be soaked in a denture cleaner, such a Polident.  Follow the directions on the box of denture cleaner.  Typically, I discourage soaking dentures in denture cleaner overnight unless you have particular problem with denture staining.  Denture cleaners, by themselves, will not clean your denture.  However, they are effective in removing denture stain.  Long term soaking, night after night, in some harsh denture cleaners can cause deterioration of the denture acrylic.

Do not soak your dentures in bleach.  Bleach will heavily tarnish the metal of a partial denture and long term use will weaken the denture acrylic.

Between brushings, it's important to rinse your dentures after each meal.  Even if you have a full set of dentures, it's important to keep your gums and tongue clean. Be sure to use a soft-bristled brush to gently clean your gums and tongue every day.